Life Sciences
DisCo: boosting the efficiency of single-cell RNA sequencing
Research
EPFL
Bioengineers at EPFL have found a way to radically increase the efficiency of single-cell RNA-sequencing, a powerful tool that can “read” the genetic profile of an individual cell.
Revealing the genetic code of Europe’s species diversity
Research
Eawag
Scientists from 48 countries initiated the “European Reference Genome Atlas” at the start of 2021. Within this project, around 600 researchers aim to decode the genetic repertoire of all species of the continent by generating reference genomes for the roughly 200,000 eukaryotic species. The hope is to strengthen the foundations for conservation of biodiversity.
Blocking sphingolipids counteracts muscular dystrophy
Research
EPFL
EPFL scientists have made the first link between muscular dystrophy and a group of bioactive fats, the sphingolipids, which are involved in numerous cell functions and other diseases.
Neutral mutants can prevail in gut microbiota, enhancing diversity
Research
EPFL
Scientists at EPFL and Sorbonne propose a new model of the diversity and evolution of gut bacteria that shows how the gut environment helps neutral mutations become prevalent, with significant potential implications on health and metabolic diseases.
Shape guides the growth of organoids
Research
EPFL
Organoids are miniature lab-grown tissue structures that can mimic real organs. But guiding stem cells to grow an organoid of defined shape and size is difficult. Now, EPFL bioengineers have developed new methods for successfully guiding the stem cells to grow into intestinal tissues with real-life 3D structure and function.
A deep look into Huntington's brain aggregates
Research
EPFL
A new study from EPFL reveals novel insights into the ultrastructure and biochemical composition of huntingtin aggregates, the mark of Huntington’s disease, pointing to new avenues for treatment strategies.
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