Genetics

Researchers from EPFL and the University of Geneva (UNIGE) have gained new insights into a mechanism regulating the early-stage development of mouse embryos. Instead of using an animal model, the team carried out their research on pseudo-embryos grown in the lab from stem cells.

In theory, the genetic diversity of populations should decrease as they expand across space. But this is not true for bacteria. Researchers at Eawag are now showing that fungi play an important role in this context. They make it easier for bacteria to spread and thus also promote genetic exchange between different bacteria.

Can microbes from cold alpine soils break down plastic? This has been investigated in a study carried out by the Swiss Federal Institute for Forest, Snow and Landscape Research WSL. Such organisms could help break down and recycle plastic in the future.

A new study by scientists at the NeuroRestore research center has identified the type of neuron that is activated and remodeled by spinal cord stimulation, allowing patients to stand up, walk and rebuild their muscles – thus improving their quality of life. This discovery, made in nine patients, marks a fundamental, clinical breakthrough. The study was published today in Nature.

EPFL scientists have discovered a rare gene in the tumors of some colorectal cancer patients. This finding could lead to more accurate diagnoses and, eventually, personalized treatments that target the protein expressed by the gene.

EPFL spin-off Alithea Genomics has developed a system that allows scientists to easily tag bulk RNA samples with molecular barcodes so they can be processed by the hundreds in one single tube. The technology promises to dramatically shorten and streamline sample preparation for RNA sequencing, which will enable new applications for this technology, such as biomarker discovery and drug development.